Copper complexes of a few amino acid Schiff bases have been prepared in moderate to good yield. The structures of final compounds were characterized by IR and physicochemical properties. The synthesized compounds have been checked for antiepileptic activity using MES electroshock procedure. Among all the evaluated complexes, compound C3C8 came out to be most active with 74% protection from seizures. Complexes of aromatic amino acid were more efficacious than that of aliphatic ones.
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